Compounders should keep the following guidelines in mind when compounding sterile preparations:

Thu, 03/22/2012

Compounders should keep the following guidelines in mind when compounding sterile preparations:


• As with any compounded preparations, compounding pharmacists should be licensed and in good standing with their state boards of pharmacy.
• The pharmacy should also be licensed in any other states to which it could be dispensing/distributing/providing the medication.
• Compounding pharmacists should comply with all United States Pharmacopeia USP <797> standards for sterile compounding.
• Compounders should keep in mind that the original source material is not verified to be sterile.  Compounders should conduct testing to ensure that the compounded preparation is verified to be sterile according to USP <71> Sterility Tests.
• The pharmacy should have Standard Operating Procedures (SOPs) for tracking all lots of compounds per physician order as well as SOPs for a product recall if necessary.
• Compounders may want to suggest to patients that they obtain an antibiotic prescription from their prescriber for prior & post treatment of receiving their ocular medication in order to minimize potential of infection.
• It’s recommended that patients also should ask the practitioner administering the ocular medication to wear appropriate masking to avoid potential of oral flora which could cause infection.  Please click here for more information.